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** Gastrointestinal Hemorrhage (Incidence: 2.0%) ** Cerebral Hemorrhage (Incidence: 0.1 to 0.4%) References * Chan FKL, Ching JYL, Hung LCT, Wong VWS, Leung VKS, Kung NNS, et al. Clopidogrel versus aspirin and esomeprazole to prevent recurrent ulcer bleeding.

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Adverse effects Serious adverse drug reactions associated with clopidogrel therapy include: * Severe neutropenia (Incidence: 5/10,000) * Thrombotic thrombocytopenic purpura (TTP) (Incidence: 4/1,000,000 patients treated) * Hemorrhage - The incidence of hemorrhage may be increased by the co- administration of aspirin.

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